Fluorescence imaging in the NIR-I will offer information to a surgeon that is invisible to the naked eye such as tissue perfusion or lymphatic drainage efficiency.
It is foreseen that the NIR-2 window imaging technique currently used for pre-clinical studies will be gaining momentum as it will potentially allow better tissue penetration and a reduced auto fluorescence background. This will also allow better discriminate weak reflectance signals emitted by tumours versus healthy tissue, thus enabling more accurate safety margins during surgical interventions.